Intramuscular cimetidine is safe and acceptable.

Intramuscular cimeti- dine and ranitidine as prophylaxis against gastric aspiration

Preoperative cimetidine 300 mg or ranitidh~e in 50 and 100 mg doses were administered intramuscularly to 120 patients in a randomized double-blind study. The volume and pH of gastric aspirate samples obtained after tracheal intubation and before extabation were measured. The pH of gastric aspirate was higher Jbllowing ranitidine 100 mg than ranitidine 50 mg or cimetidine 300 mg at both intubati...

The effect of oral Bicitra compared with intramuscular cimetidine on gastric volume and pH in outpatient surgery.

Controlled trial of maintenance cimetidine treatment in healed duodenal ulcer: short and long-term effects.

Forty-two patients with endoscopically diagnosed duodenal ulcer were studied in a double-blind trial after their ulcers had been healed with cimetidine. Cimetidine was effective in preventing relapse, only five of the 20 patients allocated to cimetidine 400 mg twice daily relapsing during the six months' treatment, compared with 16 of the 22 on placebo treatment (P less than 0.01). Cimetidine w...

Male sexual dysfunction during treatment with cimetidine.

It has been suggested that the histamine H2-receptor antagonist cimetidine, which is widely used in the management of duodenal ulcer, should be used mainly for long-term treatment of this disease., Continuous treatment with cimetidine is thought to be safe, since the documented toxicity is low. Nevertheless, we describe here three patients who developed sexual dysfunction while being treated wi...

Effect of cimetidine on upper gastrointestinal bleeding after renal transplantation: a prospective study.

In 97 consecutive patients undergoing renal transplantation the incidence of upper gastrointestinal bleeding was registered over 180 days after allocation to treatment with either cimetidine or placebo. Bleeding episodes occurred in 12 patients, 11 of whom were receiving placebo and only one cimetidine (p less than 0.01). All bleeding episodes occurred during the first month after allotransplan...